Jayaprakasam Bolleddula Selected Research

Hematologic Neoplasms (Hematological Malignancy)

1/2021

Phase I study assessing the mass balance, pharmacokinetics, and excretion of [14C]-pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumors.

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Jayaprakasam Bolleddula Research Topics

Disease

5	Neoplasms (Cancer) 01/2022 - 10/2020
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2024
1	Multiple Sclerosis 12/2023
1	Hematologic Neoplasms (Hematological Malignancy) 01/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021
1	Colorectal Neoplasms (Colorectal Cancer) 10/2020
1	Inflammation (Inflammations) 09/2013
1	Asthma (Bronchial Asthma) 09/2013
1	Pneumonia (Pneumonitis) 09/2013

Drug/Important Bio-Agent (IBA)

2	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2022 - 01/2021
2	pevonedistatIBA 01/2022 - 01/2021
2	EnzymesIBA 01/2022 - 01/2021
1	Proteins (Proteins, Gene)FDA Link 01/2024
1	Phosphotransferases (Kinase)IBA 01/2024
1	evobrutinibIBA 12/2023
1	Agammaglobulinaemia Tyrosine KinaseIBA 12/2023
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2021
1	Cytochrome P-450 CYP3AIBA 01/2021
1	ivosidenibIBA 01/2021
1	aniline (aniline hydrobromide)IBA 11/2020
1	Cathepsin BIBA 11/2020
1	DNA (Deoxyribonucleic Acid)IBA 11/2020
1	indusatumabIBA 10/2020
1	auristatinIBA 10/2020
1	AntigensIBA 09/2013
1	Immunoglobulin E (IgE)IBA 09/2013
1	Interleukin-4 (Interleukin 4)IBA 09/2013
1	Interleukin-13IBA 09/2013
1	FlavonoidsIBA 09/2013

Therapy/Procedure

2	Intravenous Administration 01/2022 - 10/2020
1	Intravenous Infusions 01/2022
1	Drug Therapy (Chemotherapy) 01/2021